Figure 2

A scatter plot comparing the fluorescence intensity in tumor and the adjacent normal CAM tissue was compiled from 1 – 5 h post topical drug administration. The points on the scatter plot are normalized individual measurements from 24 eggs. The dotted line is the cut-off fluorescence intensity threshold derived from the ROC curve to classify tumor from normal tissue with a sensitivity and specificity of 70.8% (95% CI 48.9% to 87.4%) and 83.3% (95% CI 62.6% to 95.3%) respectively.