Fig. 4

Global circumferential and radial strain curves of three subjects from different study groups in the ACDC dataset. The curves were plotted as a function of normalized time. The end-diastolic and end-systolic mid-ventricular images of each subject are shown at the top of each column. Normally, the strain at the end of the cardiac cycle should be nearly zero due to the periodicity of the cardiac motion. However, in the presence of the drift effect, the estimated late-diastolic strain can be significantly different from zero, which is observed for the Farneback optical flow and pairwise registration but not for the groupwise methods. ED = end-diastolic; ES = end-systolic; DCM = dilated cardiomyopathy; MI = myocardial infarction; NOR = normal cardiac anatomy and function; GCS = global circumferential strain; GRS = global radial strain