Table 1 Patient clinical characteristics
Characteristics | Non-SMAD4-mutated PDAC (n = 204) | SMAD4-mutated PDAC (n = 224) | P value |
|---|---|---|---|
Age | 64.74 ± 9.27 | 64.57 ± 9.03 | 0.850 |
Sex | Â | Â | Â |
   Male | 115(56.37%) | 131(58.48%) | 0.659 |
   Female | 89(43.63%) | 93(41.52%) |  |
BMI | 22.69 ± 3.16 | 22.82 ± 3.26 | 0.708 |
Diabetes | Â | Â | 0.247 |
   Absence | 148(72.55%) | 151(67.41%) |  |
   Presence | 56(27.45%) | 73(32.59%) |  |
HBP | Â | Â | 0.647 |
   Absence | 113(55.39%) | 129(57.59%) |  |
   Presence | 91(44.61%) | 95(42.41%) |  |
CA19-9 (U/mL) | Â | Â | 0.010 |
   > 100 | 94(46.08%) | 76(33.93%) |  |
   ≤ 100 | 110(53.92%) | 148(66.07%) |  |
TBil (µmol/L) |  |  | 0.245 |
   > 20.4 | 65(31.86%) | 83(37.05%) |  |
   ≤ 20.4 | 139(68.14%) | 140(62.5%) |  |
Albumin (g/L) | Â | Â | 0.373 |
   > 37 | 169(82.84%) | 178(79.46%) |  |
   ≤ 37 | 35(17.16%) | 46(20.54%) |  |
T stage | Â | Â | 0.427 |
   T1 | 62(30.39%) | 58(25.89%) |  |
   T2 | 109(53.43%) | 136(60.71%) |  |
   T3 | 32(15.69%) | 28(12.5%) |  |
   T4 | 4 (0.49%) | 1 (0.9%) |  |
N stage | Â | Â | 0.527 |
   N0 | 120(58.82%) | 122(54.46%) |  |
   N1 | 73(35.78%) | 85(37.95%) |  |
   N2 | 11(5.39%) | 17(7.59%) |  |
Resection margin | Â | Â | 0.180 |
   R0 | 199(97.55%) | 213(95.09%) |  |
   R1 | 5(2.45%) | 11(4.91%) |  |