Table 3 Uni- and multi-variate analyses for predictive factors for SMAD4 mutation of PDAC

Age

1.002 (0.981, 1.023)

0.849

Sex [Male]

0.917 (0.625, 1.346)

0.659

BMI

1.011 (0.953, 1.073)

0.707

Diabetes[present]

1.278 (0.843, 1.936)

0.248

HBP [present]

0.914 (0.624, 1.341)

0.647

CA19-9 [> 100 U/mL]

1.631 (1.105, 2.409)

0.014

1.519 (1.017, 2.268)

0.041

TBil (µmol/L) [> 20.4 µmol/L]

1.268 (0.849, 1.892)

0.246

Albumin [> 37 g/L]

1.248 (0.766, 2.032)

0.373

Resection margin [R1]

2.055 (0.702, 6.020)

0.189

Location [Head]

0.823 (0.559, 1.213)

0.326

Size

1.011 (0.847, 1.208)

0.900

Margin [Ill-defined]

1.516 (1.025, 2.242)

0.037

1.283 (0.845, 2.377)

0.242

Signal in T2-weighted images [Hyperintense]

1.126 (0.707, 1.783)

0.618

Signal in DWI [Hyperintense]

1.190 (0.761, 1.863)

0.446

Unenhanced T1-weighted imaging [Hypointense]

1.173 (0.607, 2.266)

0.635

API at MRI [Hypointense]

1.156 (0.650, 2.055)

0.622

VPI at MRI [Hypointense]

0.946 (0.632, 1.415)

0.787

DPI at MRI [Hypointense]

1.135 (0.776, 1660)

0.513

MPD dilation [present]

0.900 (0.588, 1.377)

0.628

CBD dilation [present]

1.567 (1.050, 2.338)

0.028

1.564 (1.029, 2.268)

0.036

IBD dilation [present]

1.211 (0.811, 1.809)

0.349

Peripancreatic fat infiltration [present]

0.995 (0.614, 1.611)

0.983

Pancreatic atrophy [present]

0.916 (0.624, 1.344)

0.653

Cystic degeneration [present]

0.891 (0.550, 1.442)

0.891

Hemorrhage [present]

1.844 (0.455, 7.471)

0.391

Necrotic [present]

1.538 (1.031, 2.296)

0.035

1.224 (0.773, 1.939)

0.388

Enlarged lymph nodes at imaging [present]

0.967 (0.631, 1.481)

0.877

ADC (×10^− 3 mm²/s)

1.142 (0.714, 1.827)

0.578

Rim enhancement [present]

1.815 (1.236, 2.664)

0.002

1.631 (1.064, 2.498)

0.025