Diffusion-weighted MRI-Derived ADC and tumor volume as predictive imaging markers for neoadjuvant chemotherapy response in muscle-invasive bladder cancer

Table 3 Comparison of percent changes in mid-treatment parameters between patients with and without clinical complete response to chemotherapy

Mid-treatment Variables	Patient group		Between-group difference	P
Mid-treatment Variables	CR	No CR	Between-group difference	P
ΔADC%_{single−slice}	37.33 (11.58)	22.90 (6.64)	14.43 (13.35)	0.672
ΔADC%_{whole−lesion}	33.92 (10.86)	21.26 (5.79)	12.66 (12.31)	0.766
ΔTV%	-54.73 (15.34)	-45.60 (9.26)	-9.13 (17.00)	0.191
	OR	No OR
ΔADC%_{single−slice}	37.18 (9.26)	18.84 (7.51)	18.34 (11.92)	0.281
ΔADC%_{whole−lesion}	34.54 (8.92)	16.99 (5.96)	17.54 (10.72)	0.299
ΔTV%	-56.67 (12.36)	-40.70 (10.71)	-15.96 (16.76)	0.100

CR, complete response; OR, overall response; ADC, apparent diffusion coefficient; TV, tumor volume; ΔADC% and ΔTV% were reported as mean % (SEM)

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