Table 3 The diagnostic efficacy parameters of the three criteria for PCa in the [18F]DCFPyL PET/CT
[18F]DCFPyL group (n = 55) | SUVmax | miPSMA score | PSMA-RADS | |||
|---|---|---|---|---|---|---|
Pathology | Positive (n = 43) | Negative (n = 12) | Positive (n = 43) | Negative (n = 12) | Positive (n = 44) | Negative (n = 11) |
PCa (n = 44) | 42 | 2 | 42 | 2 | 42 | 2 |
BPD (n = 11) | 1 | 10 | 1 | 10 | 2 | 9 |
Sensitivity (95% CI) | 95.45% (89.30%, 100%) | 95.45% (89.30%, 100%) | 95.45% (89.30%, 100%) | |||
Specificity (95% CI) | 90.91% (73.92%, 100%) | 90.91% (73.92%, 100%) | 81.82% (59.03%, 100%) | |||
Accuracy (95% CI) | 94.55% (88.55%, 100%) | 94.55% (88.55%, 100%) | 92.73% (85.87%, 99.59%) | |||
Mistake diagnostic rate (95% CI) | 9.09% (0%, 26.08%) | 9.09% (0%, 26.08%) | 18.18% (0%, 40.97%) | |||
Omission diagnostic rate (95% CI) | 4.55% (0%, 11.21%) | 4.55% (0%, 11.21%) | 4.55% (0%, 11.21%) | |||
Positive predictive value (95% CI) | 97.67% (93.16%, 100%) | 97.67% (93.16%, 100%) | 95.45% (89.30%,100%) | |||
Negative predictive value (95% CI) | 83.33% (62.24%, 100%) | 83.33% (62.24%, 100%) | 81.82% (59.03%, 100%) | |||
Youden Index (95% CI) | 86.36% (77.29%, 95.43%) | 86.36% (77.29%, 95.43%) | 77.27% (66.19%, 88.35%) | |||
AUC (95% CI) | 96.49% (91.54%, 100%) | 96.28% (91.88%, 100%) | 89.87% (80.40%, 99.35%) | |||