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Table 1 Risk of bias assessment using the ROBINS-I tool

From: Investigating the significance of SPECT/CT-SUV for monitoring 177Lu-PSMA-targeted radionuclide therapy: a systematic review

Bias

Wang et al. (2019) [52]

Pathmanandavel et al. (2023) [54]

Grkovski et al. (2023) [55]

Song et al. (2024) [51]

Neubauer et al. (2024) [53]

SPECT/CT reconstruction process (SUV phantom validation)

Intermediate

Intermediate

Low

High

High

Selection (study type and sample size)

High

Low

Intermediate

Intermediate

Intermediate

Missing outcome data (SUV metrics)

Low

Low

Low

Low

Low

Measurement of the outcome

Low

Low

Low

Low

Low

Selection of the reported result

Low

Low

Low

Low

Low

Overall ROBINS-I (low = 1, intermediate = 2, high = 3)

1.6

1.2

1.2

1.6

1.6