A short-term predictive model for disease progression in acute-on-chronic liver failure: integrating spectral CT extracellular liver volume and clinical characteristics

Table 2 Comparison of SMI and Liver Spectral CT parameters between two groups of patients with ACLF, along with ICC for measurements by two radiologists

SMI and liver spectral CT parameters	Progressive Group (n = 70)	Stable Group (n = 56)	T/U/ c²	P Value	ICC
L3-SMI (cm²/m²)	40.5 ± 6.7	44.9 ± 5.9	3.856	<0.001	0.889
IC-EP (100 µg/cm³)	20.6 (18.2, 26.1)	18.8 (16.5, 23.8)	-2.286	0.022	0.912
Z-EP	8.8 (8.7, 9.1)	8.7 (8.6, 8.9)	-2.298	0.020	0.907
K₁₄₀-EP	1.6 (1.5, 2.0)	1.5 (1.3, 1.8)	-2.227	0.026	0.913
NIC-EP	0.6 (0.5, 0.6)	0.5 (0.5, 0.6)	-3.511	<0.001	0.926
ECV_IC−liver	40.6 (38.8, 41.8)	31.4 (29.3, 34.8)	-6.076	<0.001	0.917

ACLF, Acute-on-chronic liver failure; L3-SMI, Skeletal muscle index at L3; IC, Iodine concentration; EP, Equilibrium phase; Z, Effective atomic number; K₁₄₀, Energy spectrum curve slope; NIC, Normalized iodine concentration; ECV_IC−liver, Extracellular liver volume; ICC, Intraclass correlation coefficient

ISSN: 1471-2342