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Table 1 Comparison of prognosis and clinical baseline characteristics between the training and validation cohorts

From: Machine learning prediction model for functional prognosis of acute ischemic stroke based on MRI radiomics of white matter hyperintensities

Variables

Training cohort(n = 141)

Validation cohort(n = 61)

t/χ2/Z

P

Age (years)

70.05 ± 9.47

69.87 ± 7.30

0.133

0.894

Infarct volume (cm3)

4.58(3.16,7.69)

4.38(2.53,6.94)

-1.097

0.273

Gender (%)

  

3.563

0.059

 Female

43(30.5)

27(44.3)

  

 Male

98(69.5)

34(55.7)

  

Hypertension (%)

  

0.356

0.551

 No

38(27.0)

14(23.0)

  

 Yes

103(73.0)

47(77.0)

  

Hyperlipidemia (%)

  

0.002

0.963

 No

132(93.6)

57(93.4)

  

 Yes

9(6.4)

4(6.6)

  

DM (%)

  

0.263

0.608

 No

99(70.2)

45(73.8)

  

 Yes

42(29.8)

16(26.2)

  

CAD (%)

  

1.418

0.234

 No

97

47

  

 Yes

44

14

  

Stroke history (%)

  

0.454

0.500

 No

72(51.1)

28(45.9)

  

 Yes

69(48.9)

33(54.1)

  

Smoking history (%)

  

0.097

0.755

 No

101(71.6)

45(73.8)

  

 Yes

40(28.4)

16(26.2)

  

Drinking history (%)

  

0.807

0.369

 No

105(74.5)

49(80.3)

  

 Yes

36(25.5)

12(19.7)

  

Systolic blood pressure (mmHg)

154.58 ± 22.60

152.25 ± 22.26

0.677

0.499

Diastolic blood pressure (mmHg)

88.51 ± 12.69

86.62 ± 13.01

0.964

0.336

Admission blood glucose (mmol/L)

7.15(5.26,8.79)

6.77(5.13,8.62)

-0.703

0.482

HbA1c (%)

6.10(5.75,7.30)

6.30(5.70,7.65)

-0.563

0.574

TC (mmol/L)

4.55(3.69,5.25)

4.25(3.69,4.80)

-1.214

0.225

TG (mmol/L)

1.28(0.87,1.76)

1.22(0.83,1.83)

-0.222

0.825

HDL (mmol/L)

1.17(0.97,1.34)

1.10(0.88,1.22)

-1.993

0.056

LDL (mmol/L)

2.77(2.02,3.34)

2.52(2.04,3.02)

-1.459

0.145

HCY (µmol/L)

13.79(11.28,18.94)

12.09(10.28,18.31)

-1.467

0.142

Prognosis (%)

  

0.047

0.828

 Good (mRS 0–2)

74(52.5)

31(50.8)

  

 Poor (mRS 3–6)

67(47.5)

30(49.2)

  
  1. Abbreviations: t: t-test; Z: Mann-Whitney test; χ²: Chi-square test; DM: Diabetes mellitus; CAD: coronary artery disease; HbA1c: Hemoglobin A1c; TC: total cholesterol; TG: triglyceride; HDL: high density lipoprotein; LDL: low density lipoprotein; HCY: homocysteine; mRS: the modified Rankin Scale