Table 1 The demographic and clinical characteristics and macroscopic cerebral volume measurements of all participants
|  | MwA (n = 32) | MwoA (n = 56) | HC (n = 49) | Patients versus HCs p-valuea | MwA versus MwoA p-valuea |
|---|---|---|---|---|---|
Age (years) | 35.4 ± 12.1 | 37.0 ± 8.9 | 37.4 ± 8.9 | 0.56 | 0.48 |
Gender (Male/Female) | 7/25 | 11/45 | 16/33 | 0.11b | 0.80b |
Disease duration (years) | 11.8 ± 8.7 | 14.4 ± 8.8 | NA | NA | 0.19 |
Frequency (days per month) | 4.1 ± 4.0 | 5.4 ± 6.6 | NA | NA | 0.35 |
Headache severity score | 6.0 ± 1.4 | 4.3 ± 1.2 | NA | NA | < 0.01 |
Cortical gray matter volume (mm3) | 432553.6 ± 22598.4 | 440723.2 ± 38454.2 | 432320.8 ± 25861.6 | > 0.1 | > 0.1 |
Subcortical gray matter volume (mm3) | 59687.6 ± 3591.8 | 61099.4 ± 5889.6.8 | 59370.4 ± 6388.5 | > 0.1 | > 0.1 |
Total gray matter volume (mm3) | 582754.2 ± 31497.8 | 602319.5 ± 49657.5 | 592792.6 ± 44949.8 | > 0.1 | > 0.1 |
Total brain volume (mm3) | 1209944.5 ± 209687.7 | 1273486.6 ± 231421.3 | 1277152.6 ± 261605.0 | > 0.1 | > 0.1 |