Assessment of right ventricle–to–pulmonary artery coupling by three-dimensional echocardiography in pre-capillary pulmonary hypertension: comparison with tricuspid annular plane systolic excursion /systolic pulmonary artery pressure ratio

Table 3 Key results before and after PEA

Variables	Before PEA	After PEA	P
Echocardiography
RA area (cm²)	29.0 ± 13.6	21.1 ± 8.0	<0.001
RV basal diameter (mm)	47.7 ± 7.5	39.6 ± 5.3	<0.001
RV/LV basal diameter	1.4 ± 0.5	1.0 ± 0.2	<0.001
TAPSE (mm)	16.5 ± 3.7	11.8 ± 2.0	<0.001
S’ (cm/sec)	10.9 ± 2.8	9.1 ± 2.0	0.025
FAC (%)	25.8 ± 8.7	36.8 ± 6.0	<0.001
3DE RV SV mL/m²	36.9 ± 10.0	28.0 ± 9.5	0.004
3DE RV ESV mL/m²	81.4 ± 29.6	40.6 ± 21.0	<0.001
3DE RV EDV mL/m²	118.3 ± 36.7	69.0 ± 29.0	<0.001
3DE RVEF(%)	32.2 ± 7.0	42.6 ± 7.9	<0.001
3DE SV/ESV	0.44 ± 0.12	0.71 ± 0.24	<0.001
TAPSE/sPAP	0.20 ± 0.10	0.30 ± 0.08	0.006
Right heart catheterization
PVR(Wood Units)	13.7 ± 7.0	7.0 ± 3.2	0.001
mPAP (mmHg)	47.1 ± 10.5	29.1 ± 8.7	0.004

Changes in right heart catheterization and echocardiographic parameters before and after PEA were analyzed using paired t tests
RA area: right atrium area; RV/LV basal diameter: ratio of right ventricular and left ventricular basal diameter; TAPSE: tricuspid annular plane systolic excursion; S’: systolic velocity of the tricuspid lateral annulus; FAC: fractional area change; 3DE: three-dimensional echocardiography; RV EDV: right ventricular end-diastolic volume; RV ESV: right ventricular end-systolic volume; RV SV: right ventricular stroke volume; RV EF: right ventricular ejection fraction; SV/ESV: storke volume/end-systolic volume; mPAP: mean pulmonary artery pressure; PVR: pulmonary vascular resistance

ISSN: 1471-2342