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Table 2 Univariate analysis to differentiate between high and low Ki-67 PI groups in the training set

From: Radiomics analysis of dual-layer detector spectral CT-derived iodine maps for predicting Ki-67 PI in pancreatic ductal adenocarcinoma

Variables

High Ki-67 PI group (Ki-67 PI ≥ 50%, n = 35)

Low Ki-67 PI group (Ki-67 PI < 50%, n = 83)

F/Z/c²

p

Age, y

65(58,70)

22.49(21.33,24.31)

−1.182

0.237

BMI

22.49(21.33,24.31)

21.87(20.80,24.72)

−0.884

0.377

Gender, n (%)

  

3.619

0.391

 Male

67(56.8)

28(56.0)

  

 Female

51(43.2)

22(44.0)

  

CA19-9, n (%)

  

84.828

<0.001

 Normal

47(39.8)

13(26.0)

  

 Elevated

71(60.2)

37(74.0)

  

CEA, n (%)

  

5.503

0.205

 Normal

90(76.3)

32(64.0)

  

 Elevated

28(23.7)

18(36.0)

  

CA125, n (%)

  

1.268

0.543

 Normal

79(66.9)

31(62.0)

  

 Elevated

39(33.1)

19(38.0)

  

CT-reported T stage

  

2.795

0.275

 T1-2

45(38.1)

17(34.0)

  

 T3-4

73(61.9)

33(66.0)

  

CT-reported regional LN status

    

 Negative

65(55.1)

29(58.0)

3.990

<0.001

 Positive

53(44.9)

21(42.0)

  

vascular invasion

  

12.993

0.056

 Negative

53(44.9)

18(36.0)

  

 Positive

65(55.1)

32(64.0)

  

extrapancreatic perineural invasion

  

28.635

0.029

 Negative

41(34.7)

12(24.0)

  

 Positive

77(65.3)

38(76.0)

  

Radiomics signature

3.75 ± 2.79

−3.67 ± 4.66

3.656

<0.001

  1. BMI, body mass index; PI, proliferation index; CA125, carbohydrate antigen 125; CA19-9, carbohydrate antigen 19–9; CEA, carcinoembryonic antigen; LN lymph node