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Table 3 The research specifics on disease diagnosis based on medical imaging using ensemble AI

From: A systematic literature review: exploring the challenges of ensemble model for medical imaging

Authors (Year)

Algorithms

Modality

Performances

Domain

Baseline

Fusion

Ko et al. (2019) [23]

RetinaNet & Mask R-CNN

Weighted voting ensemble

25,684 chest x-ray (CXR) images & 28,989 lung opacity bounding boxes

Mean average precision (mAP): 0.21746

Pneumonia detection

Livieris et al. (2019)[49]

SMO, C4.5, & kNN

Weighted voting ensemble

5830 chest x-ray (Pneumonia), 566 lung mask (Tuberculosis), &

100 CT medical

Accuracy: Pneumonia 82.53–83.49%, Tuberculosis 69.79–71.73%, and CT medical 69–77%

Detecting lung abnormalities from chest X-rays

Brunese et al. (2020)[46]

First order, shape, gray level co-occurrence matrix, gray level run length matrix & gray level size zone matrix

Weighted voting ensemble

111,205 radiomic features extracted from MRI images

Accuracy of 99%

The benign grade I and the II, III, and IV malignant brain cancer detection

Deb and Jha (2020)[24]

NASNet, MobileNet & DenseNet

Ensemble

Chest x-rays

Accuracy of 91.99%

COVID-19 detection into 3 classes: Community Acquired Pneumonia (CAP), normal, & COVID-19.

Mao et al. (2020)[25]

RetinaNet & Mask R-CNN

Weighted average ensemble

26,684 chest x-rays

Precision of 0.808, recall of 0.813, and mAP of 0.2283

Detect pneumonia

Suhail et al. (2020)[26]

Logistic regression & neural networks

Random forest ensemble

287 cephalometric x-rays

Accuracy: primary or alternative outcome agreement 93–98%

Predicting orthodontic extractions

Chandra et al.(2021) [27]

ANN, KNN, NB, DT, SVM-linear kernel, SVM-radial basis function, & SVM-polynomial kernel

Majority voting ensemble

2346 chest x-rays

Accuracy of 93.41%

Automatic COVID screening (ACoS) system

Golla et al.(2021) [44]

2D and 3D versions of U-Net, V-Net, & DeepVesselNet

Ensemble

Abdominal CT scans

Dice similarity coefficients (DSC) of 0.758 for veins and 0.838 for arteries

Artery and vein segmentation

Jiang et al. (2021) [45]

RRC model & 3D-CNN models

XGBoost ensemble

CT images: 7302 radiomic features and 17 radiological from 405 patients

AUROC 0.887–0.906

Predicting MVI in HCC patients

Jin et al. (2021) [28]

AlexNet, ReliefF, & SVM

Hybrid ensemble

1743 chest x-rays

Overall accuracy rate: 98.642 ± 0.398%

Diagnosis between COVID-19, common viral pneumonia, and normal

Rahman et al. (2021) [29]

ResNet101, VGG19, & DenseNet201

XGBoost ensemble

7000 chest x-rays

Accuracy of 99.92%, precision of 99.85%, & sensitivity of 100%

Detect tuberculosis (TB) and normal

Sagor et al. (2021) [30]

Inception-v3, VGG16, & ResNet-50

XGBoost ensemble

112,120 chest x-rays

Accuracy of 88.14%

Detecting lung disease

Tao et al. (2021) [14]

AlexNet, GoogleNet, & ResNet.

Relative majority voting ensemble

7,500 lung CT images

Accuracy of 99.05%

Detecting COVID-19 between lung tumor and normal lung

Bui et al. (2022) [31]

VGG, Resnet, Xception, & SVM

Majority voting ensemble

95 Panoramic x-rays generate 533 tooth regions

Accuracy of 93.58%, sensitivity of 93.91%, & specificity of 93.33%

Automated caries screening

Gokul et al. (2022) [32]

CAPSNet & VDSNet

Snapshot ensemble

5,856 chest x-rays

Accuracy, precision, specificity: 0.98 & recall: 0.96

Pneumonia diagnosis between pneumonia and normal class

Imak et al. (2022) [33]

Multi-input AlexNet

Scored-based fusion ensemble

340 periapical x-rays

Accuracy of 99.13%

Caries detection between caries and non caries class

Iqball and Wani (2022) [34]

ResNet101, InceptionV3, MobileNetV2, NasNet, & Xception

Weighted sum ensemble

1,088 chest x-rays

Accuracy, precision, recall: 100%

Pneumonia detection between COVID-19, pneumonia, normal

Jaiswal et al. (2022) [35]

ResNet50V2, ResNet101V2, MobileNetV3Small, MobileNet, MobileNetV3Large, EfficientNetB0, EfficientNetB1, & EfficientNetB2

XGBoost ensemble

500 panoramic x-rays

Accuracy: tooth wear 91.8%, periapical 92.2%, periodontitis 92.4%, tooth decay 93.2%, missing tooth 91.6%, and impacted tooth 90.8%

Multi oral disease classification: tooth wear, periapical, periodontitis, tooth decay, missing tooth, and impacted tooth

Muller et al. (2022) [50]

DenseNet121, EfficientNetB4, InceptionResNetV2, MobileNetV2, ResNeXt101, ResNet101, VGG16, Xception, & Vanilla architecture

Augmenting, bagging, & stacking ensemble

5,000 CHMNIST (histology), 2,905 COVID (X-ray), 25,331 ISIC (dermoscopy), & 35,126 DRD (ophthalmoscopy)

Average accuracy: CHMNIST 98%, COVID 96%, ISIC 92.75%, & DRD 81.5%

Medical image classification: CHMNIST, COVID, ISIC, and DRD

Alsubai (2023) [36]

Principle Component Analysis (PCA) & Chi-square (chi2)

Stacking ensemble (Extreme gradient boosting (XGB), random forest (RF), & extra trees classifier (ETC))

10,375 bitewing x-rays

Accuracy: 97.36%, precision: 96.14%, recall: 96,84%, & F1 score: 96.65%

Enhancing prediction of tooth caries and tooth normal

Azhari et al. (2023) [37]

ResNet50, ResNext101, & Vgg19

Ensemble U-Nets

771 bitewing x-rays: adult 554 & pediatric 217

IoU averaged of adult: zero 98%, primary 23%, moderate 19%, & advanced carious lesions 51%

IoU averaged of pediatric: zero 97%, primary 8%, moderate 17%, & advanced carious lesions 25%

Detection of interproximal carious lesions on primary and permanent dentition

Bhatt and Shah (2023) [38]

3 CNN models with kernel sizes: 3×3, 5×5, & 7×7

Weighted ensemble

5,863 chest x-rays

Accuracy, recall, precision, & F1 score: 99.23%

Pneumonia detection between pneumonia and normal

Haghanifar et al. (2023) [39]

CNN, InceptionNet, Encoder, & CheXNet,

PaXNet (Capsule network ensemble)

470 panoramic x-rays where the teeth total is 1229; 616 maxillary & 613 mandibular

Accuracy: 81.44% maxilla & 73.67% mandible

Tooth segmentation and dental caries detection: healthy and carious

Mabrouk et al. (2023) [40]

DenseNet169, MobileNetV2, & Vision Transformer

Ensemble learning

5,856 chest x-rays

Accuracy: 93.91%, precision: 93.96%, recall: 92.99%, & F1 score: 93.43%

Pneumonia detection between pneumonia and normal

Nakata and Siina (2023) [47]

16 CNNs (Xception, InceptionV3, InceptionResNetV2, ResNet50 & 101, ResNeXt50 & 101, SeResNetXt50 & 101, EfficientnetB0-B6)

Soft voting, weighted average voting, weighted hard voting, & stacking ensemble

Ultrasound images: 6320 benign liver tumor (BLT), 2320 liver cyst (LCY), 9720 metastatic liver cancer (MLC), 7840 primary liver cancer (PLC)

Best ROC AUC: 0.944 BLT, 0.999 LCY, 0.891 MLC, & 0.903 PLC

Multiclass classification of ultrasound images of liver masses

Paul and Naskar (2023) [41]

DenseNet169, VGG16, & InceptionV3

Soft voting ensemble

5,856 children’s lung chest x-ray

Accuracy of 92.79%

Children’s pneumonia detection between pneumonia and normal

Tareq et al. (2023) [48]

YOLO v5s, v5m, v5l, & v5x, ResNet50, VGG16, & DenseNet3

Ensemble

233 de-identified anterior teeth specimens and 1703 after augmentation

Accuracy of 86.96%

Visual diagnostics of dental caries

Dang et al. (2024) [51]

Deep neural networks (VGG16, ResNet34, & ResNet101)

Weighted ensemble

Medical image: 300 CVC-ColonDB, 912 CVC-EndoSceneStill-2017, 808 MICCAI2015, 1000 CAMUS-ED, & 1000 CAMUS-ES

Dice score: CVC-ColonDB 0.95, CVC-EndoSceneStill-2017 0.73, MICCAI2015 0.84, CAMUS-ED 0.94, & CAMUS-ES 0.94

Two-layer ensemble of deep learning models for medical image segmentation

Gupta et al. (2024) [42]

DenseNet201, MobileNetV2, & InceptionResNetV2

Stacked ensemble

5,216 chest x-ray

Accuracy of 94%

Precise pediatric pneumonia diagnosis between pneumonia and normal

Marginean et al. (2024) [43]

U-Net, Feature Pyramid Network, & DeeplabV3

Ensemble learning

1,000 panoramic x-rays

Accuracy: 99.42% & mean dice coefficient 68.2%

Teeth segmentation and carious lesions segmentation