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Table 5 Multivariable logistic regression analysis to identify the factors associated with upgrade of atypical ductal hyperplasia with intraductal papilloma at biopsy

From: Atypical ductal hyperplasia diagnosed by US-guided core needle biopsy: clinical, pathological and US features associated with upgrading to malignancy

Variable

Multivariable Analysis

Odds Ratio (95%CI)

P Value

Median age (year)

1.06(1.02,1.10)

0.005

Median size (cm)

1.69(0.80,3.58)

0.17

Lesion types

  

 Mass-like lesion

1 (reference)

 

 Non-mass-like lesion

2.88(0.58,14.25)

0.19

Margin

  

 Circumscribed

1 (reference)

 

 Not circumscribed

1.66(0.54,5.14)

0.38

Calcifications on ultrasound

  

 Absent

1 (reference)

 

 Present

2.01(0.34,11.80)

0.44

Ki-67 status

  

 Negative

1 (reference)

 

 Positive

3.75(0.79,17.79)

0.10

 Unknown

0.20(0.03,1.35)

0.10

Imaging-pathology correlation

  

 Concordant

1 (reference)

 

 Discordant

3.67(1.05,12.83)

0.04