Fig. 4

Parameter-time curves derived from SR CEUS images of benign and malignant superficial LNs post 0.5ml & 1.0 ml bolus injection of Sonovue. (A-D) MVD, FWVD, PI and FD increased over time, (E) Vel Var decreased over time, (F) Vmean did not show significant changes. *p < 0.05 showing that in malignant LNs, a 1.0 ml injection dose resulted in significantly higher MVD and FWVD compared to a 0.5 ml injection dose by SR CEUS images at 6th second