Fig. 3

Histopathologic appearance of a pulmonary track nodule 6 weeks after track sealing with gelatin sponge slurry visible on a surgical specimen (hematoxylin and eosin). (a) The acellular gelatin sponge material (star) is surrounded by a ring of non-necrotizing granulomatous tissue containing chronic inflammatory cells (arrow), mainly macrophages, within the pulmonary parenchyma (triangle). (b) Higher magnification of the inflammatory tissue adjacent to the sealant, showing the presence of multinucleated giant cells (arrow)