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Table 2 Demographic, clinical, cerebral vessels morphological and white matter hyperintensities characteristics in acute ischemic stroke patients

From: The impact of cerebral vessels morphological alteration and white matter hyperintensities burden on the one-year risk of ischemic stroke recurrence

Variables

Non-recurrence

(n = 625, 92.3%)

Recurrence

(n = 52, 7.7%)

P

Age (years)

/

65.2 ± 11.5

67.8 ± 11.0

0.12

Gender

Male

439 (70.24%)

37 (71.15%)

0.89

Female

186 (29.76%)

15 (28.85%)

Drinking

n (%)

100 (16.00%)

4 (7.69%)

0.11

Smoking

n (%)

236 (37.76%)

19 (36.54%)

0.86

Hypertension

n (%)

430 (68.80%)

36 (69.23%)

0.95

Diabetes mellitus

n (%)

242 (38.72%)

23 (44.23%)

0.43

Hyperlipidemia

n (%)

173 (27.68%)

15 (28.85%)

0.86

Atrial fibrillation

n (%)

52 (8.32%)

3 (5.77%)

0.52

Stroke subtype (TOAST)

LAA

280 (44.80%)

29 (55.77%)

0.23

CE

43 (6.88%)

6 (11.54%)

 

SVO

254 (40.64%)

14 (26.92%)

 

Other

7 (1.12%)

0 (0.00%)

 

Underdetermined

41 (6.56%)

3 (5.77%)

 

NIHSS

/

3.2 ± 2.94

3.1 ± 2.5

0.88

mRS at 90days

/

1.0 ± 1.4

0.8 ± 1.0

0.29

Thrombolysis

n (%)

44 (7.04%)

1 (1.92%)

0.16

Embolectomy

n (%)

3 (0.48%)

0 (0.00%)

0.62

Anticoagulants administered post-discharge

n (%)

20 (3.20%)

3 (5.77%)

0.33

Antiplatelets administered post-discharge

n (%)

576 (92.16%)

43 (82.69%)

0.02

Cerebral vessels morphological features

Volume (mm3)

6.3 ± 4.7

5.4 ± 2.4

0.05

Length (mm)

12.9 ± 6.7

10.9 ± 5.3

0.03

Radius (mm)

1.0 ± 0.1

1.0 ± 0.1

0.46

Tortuosity (ratio)

1.4 ± 0.1

1.4 ± 0.1

0.37

Dense (ratio)

0.008 ± 0.003

0.007 ± 0.003

0.07

Branch (count)

8.6 ± 6.1

6.8 ± 3.8

0.02

Arterial Stenosis

Normal (n, %)

315 (50.40%)

21 (40.38%)

0.15

Mild (n, %)

138 (22.08%)

11 (21.15%)

Moderate (n, %)

78 (12.48)

9 (17.30%)

Serve (n, %)

94 (15.04%)

11 (21.15%)

The volume of white matter hyperintensities volume

Whole Brain WMHs volume(mm3)

12.0 ± 8.9

14.7 ± 7.1

0.04

periventricular WMHs volume (mm3)

36.2 ± 20.7

44.0 ± 20.5

< 0.01

Deep WMH volume (mm3)

7.1 ± 7.4

8.8 ± 5.7

0.13

Left frontal lobe WMHs volume (mm3)

4.5 ± 7.5

4.5 ± 4.2

0.96

Right frontal lobe WMHs volume (mm3)

9.5 ± 12.8

12.5 ± 12.3

0.10

Left temporal lobe WMHs volume (mm3)

3.8 ± 6.9

3.9 ± 6.3

0.96

Right temporal WMHs volume (mm3)

4.2 ± 8.7

4.2 ± 8.1

0.97

Left parietal lobe WMHs volume (mm3)

7.6 ± 8.1

10.8 ± 10.2

< 0.01

Right parietal lobe WMHs volume (mm3)

9.4 ± 9.9

12.2 ± 10.2

0.05

Left occipital lobe WMHs volume (mm3)

8.8 ± 10.7

9.6 ± 9.9

0.64

Right occipital lobe WMHs volume (mm3)

4.6 ± 6.7

4.0 ± 3.3

0.56

Left cerebellum WMHs volume (mm3)

0.6 ± 0.6

0.3 ± 0.5

0.64

Right cerebellum WMHs volume (mm3)

0.6 ± 0.5

0.3 ± 0.4

0.60

Brainstem WMHs volume (mm3)

7.4 ± 0.3

5.2 ± 0.7

0.68

  1. TOAST: Trial of Org 10,172 in Acute Stroke Treatment; LAA: large artery atherosclerosis; CE: cardioembolic; SVO: small vessels occlusion; NIHSS: the National Institutes of Health Stroke Scale score; mRS: modified Rankin Scale; WMHs: white matter hyperintensities
  2. P-values: < 0.01 for values below 0.01
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BMC Medical Imaging

ISSN: 1471-2342

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